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Comprehensive genomic analyses have revealed a distinct tobacco-related mutational signature in liver tumors of smokers, characterized by cytosine-to-adenine base substitutions, dinucleotide alterations, and guanine adduct formation, patterns resembling those observed in lung and head-and-neck cancers [38,39,40]

The law was supposed to come into effect later this month, but that could be delayed as on 18 May the High Court is due to rule on the legal challenge to the legislation from the tobacco industry
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Confirm methods and chemicals used are safe and effective

[DOI] [PubMed] [Google Scholar] 96.Sharma RK, Pasqualotto FF, Nelson DR, Thomas AJ, Jr, Agarwal A