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Xylitol can help increase saliva flow and reduce cavity-causing bacteria

Direct translocation In specific examples, soluble constituents or other tiny ultrafine elements can be introduced directly into the systemic circulation, resulting in undeviating effects at distant deposition sites (145, 161)

This extreme situation has not been analyzed here as it is far from the scope of this work but guarantees future studies in an alveolar-mimicking scenario such as the one recreated in our models

[1] Aromatic amines: 4-aminobiphenyl, a group 1 carcinogen, was marginally higher in herbal cigarettes than in regular cigarettes and 1-aminonaphthalene, 2-aminonaphthalene, and 3-aminobiphenyl was lower in herbal cigarettes than in regular cigarettes

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