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Reduced paper permeability was the next most important factor, because it decreases the amount of oxygen that can diffuse through the paper during smoulder (Norman 1999)
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It further can induce -cell dysfunction due to the low antioxidant capacity of beta cells ( In vitro studies in -cells/islets and in vivo animal studies showed that ANG II causes -cell inflammation and -cell dysfunction through induction of endoplasmic reticulum stress (Urner et al., 2020)
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