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Reversibility of the smokingcortical thickness association Controlling for pack-years, gender and exact age at scanning (Model 4), positive associations were shown between cortical thickness at age 73 years and number of years since smoking the last cigarette (Figure 4a and Supplementary Table S3)

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The initial clinical sign of cadmium-induced renal lesions is tubular proteinuria, usually detected as increased urinary excretion of low-molecular-weight proteins (such as -2-microglobulin, or alpha-1 macroglobulin) or tubular enzymes such as N -acetyl-/-glucaminidase (NAG)

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Our primary finding is that exclusive current ST users had significantly elevated all-cause mortality (HR = 1.25, CI = 1.081.46), which was largely driven by elevated mortality from other causes in the younger age group (HR = 1.68, CI = 1.112.54)