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There are a few parts of the body through which smoking can initiate heartburn and GERD: Lower esophageal sphincter - Regular use of tobacco causes a deposit of nicotine in the lower esophageal sphincter, which is the regulator of food passage into the stomach

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The causes are as varied as the symptoms

Notably, CS significantly altered the salivary microbiota, increasing the abundance of genera such as Streptococcus , Prevotella , and Veillonella , while decreasing Neisseria