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( Chen, 2015 ) Histamine is metabolized or cleared from the body via two enzymes, histamine methyltransferase (HNMT) and diamine oxidase (DAO)

Each batch is further verified by mass spectrometry analysis, confirming structural integrity and consistency across production runs

Glutathione is a tripeptide composed of cysteine, glycine, and glutamate

doi: 10.18052/www.scipress.com/ILNS.76.72 111 ZaynabM.FatimaM.AbbasS.SharifY.UmairM.ZafarM

Unlike the MTHFD1 encoded enzyme that is a tri-functional enzyme harboring N 5 , N 10 -methenyl-THF (5,10-methenyl-THF) cyclohydrolase, 5,10-methylene-THF dehydrogenase, and 10-formyl-THF synthetase activities, the MTHFD1L encoded enzyme only possesses 10-formyl-THF synthetase activity