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Preclinical models showed improvements in muscle tears, tendon ruptures, ligament tears, and fracture healing

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If approved, orforglipron would be the first oral medication that directly competes with injectable GLP-1 therapies on efficacy

Botox patients should avoid lying down for 4 hours post-treatment, strenuous exercise for 24 hours, and facial massage/manipulation for several days preventing toxin migration, while peptide users face zero activity restrictions following application beyond normal absorption time

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