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Substitution of other immunosuppressants, for example, methotrexate, also fails to improve symptomatic SFN

However, there are a small but very important group of patients who cannot tolerate these present agents

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Vitamin B12 supports several important functions in the body, including: DNA synthesis Red blood cell production Nervous system function Myelin production, which helps protect nerves Energy metabolism Vitamin B12 absorption becomes more difficult with age because the body may produce less intrinsic factor, a stomach protein required for proper absorption

For example, the protein structure of gluten looks a lot like the protein structure of your thyroid gland