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iron overload in epileptic foci promotes the generation of lipid peroxides through ACSL4-mediated arachidonic acid metabolism, while decreased GPX4 activity further weakens antioxidant defenses, forming a vicious cycle of neuronal hyperexcitability-oxidative stress. Preclinical studies show that using Liproxstatin-1 to inhibit ferroptosis can significantly reduce the frequency of seizures and protect hippocampal neurons (Batista et al., 2021)

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Tetrahydrobiopterin in the treatment of children with autistic disorder: a double-blind placebo-controlled crossover study

ROS, primarily generated as byproducts of mitochondrial energy production, accumulate intracellularly due to reduced ROS clearance capacity caused by estrogen deficiency, aging, or other factors, thereby promoting OC activation (44)

It burns fat without diet or exercise. False