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Supplements / powders sold for oral use are often inappropriately used for injection and may carry bacterial/ endotoxin contamination

Patch tests on volunteers with various sterilized materials containing residues of ethylene oxide and its reaction products, showed erythema, without oedema, after 4 - 8 h of contact, from a residue level of 890 mg ethylene oxide/kg up to 2890 mg/kg of a polyvinyl chloride block

Two of the most commonly used ingredients are L-arginine and L-citrulline

Animal studies using Ebselen revealed an oxidative stress-suppressing effect (Nakamura et al

doi: 10.1111/exd.14277
