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While sometimes experts refer to the levels as doubling every few days in pregnancy, this isnt the case for everyone

23 Suppl 16: S92-6

After 24 h postplating time, fresh media were supplied (200 l/well) and treated with either an equal volume of sterile water (vehicle control) or with 23.4 mmol/l of ICA-1s

FDA PCAC 2023 What this means practically for research dosage decisions: Doses above 1 mg/day are not supported by efficacy data and appear to produce diminishing returns
