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GHKCu influences signaling related to oxidative stress and inflammation, supporting pathways that protect tissues from damage and may reduce inflammatory cytokine responses in research contexts, making it relevant for studies on aging and recovery

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Second, although emerging evidence supports a role for PDKs in tumorimmune metabolic crosstalk, studies specifically investigating PDK-mediated immunometabolic regulation in the context of cisplatin therapy remain limited

Targeting STING in cancer: Challenges and emerging opportunities

Toxicity by heavy metals, such as cadmium, lead, and mercury, can cause overproduction of ROS, oxidative stress, lipid peroxidation, inflammation, antioxidant depletion (e.g., of glutathione), disruption of astrocyte function, and protein inactivation and aggregation [93]