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The MS analysis alternated between MS and data-dependent MS n scans using dynamic exclusion, while the scan range covered m/z 701000 at a resolving power of R = 35,000 optimized at 50% of the maximum peak height (FWHM)

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Importantly, even moderate VGAT alterations, as detected in SMA mice with a modest but significant increase at both the early symptomatic and late disease stages, can significantly affect inhibitory synaptic currents and physiological responses [75]

According to the WHO report in March 2024, one out of three people globally is concerned with neurological concerns, that is, 3 billion people, which is a rise of 18% over the past few decades