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Hypothyroidism and hyperthyroidism are both severe thyroid disorders

We found no differences between the preparation conditions tested nor an effect of time to deproteinization on stability of total GSH, suggesting that use of either heparin or EDTA during sample collection can prevent enzymatic degradation of GSH when samples are stored at 80 o C

Availability: Reduced Glutathione (GSH): More widely available in various forms and brands

Structural analysis of the wild-type HsaGST A2-2 and HsaGST A3-3 shows that the steroid substrate is not binding to HsaGST A2-2 in an orientation compatible with ketosteroid isomerase activity, apparently explaining the different activities of the two enzymes (Tars et al., 2010)

however, both the age of onset and disease penetrance vary considerably among different mutations and across endemic regions [6, 7]