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This metabolic shift inhibits the conversion of glucose into acetyl-CoA, thereby preventing its entry into the tricarboxylic acid (TCA) cycle ( via solute carrier (SLC) proteins ( Glutamine metabolism is pivotal for tumor cell survival and proliferation

[DOI] [PubMed] [Google Scholar] Nakajima S, Gerretsen P, Takeuchi H, Caravaggio F, Chow T, Le Foll B, Mulsant B, Pollock B, Graff-Guerrero A (2013) The potential role of dopamine D 3 receptor neurotransmission in cognition

Similar content being viewed by others Glutamine addiction and dysregulation of the TCA cycle are characteristic features of glutamine metabolism in cancers

In Huntingtons disease (HD), oxidative stress plays a significant role in the neurodegenerative process

3c) and confirmed that Efmody improved the biochemical control of CAH by reducing the excess morning 17OHP, from 31% of patients in control at the beginning of the study to 94% after 6 months on Efmody treatment
