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E., Yen, K., & Cohen, P

However, during axon degeneration, NMNAT2 axonal transport is blocked, and the axonal pool of the protein is rapidly degraded, leading to a critical depletion of NAD + in the axon 142,143

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Tercero, 5-Amino-1MQ inhibe la NNMT, enzima que metila la nicotinamida consumiendo grupos metilo del SAM
