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In the steady state, RBC production is in equilibrium with RBC removal from circulation, which can be accomplished by two different mechanisms: hemolysis and phagocytosis by macrophages

Radiology 299 , 109119 (2021)

Moreover, oxidative stress is closely linked to diabetic complications like retinopathy, nephropathy, and cardiovascular diseases [1] (Figure 1)

Clin Neurophysiol 115:23722381 Simioni C, Zauli G, Martelli AM et al (2018) Oxidative stress: role of physical exercise and antioxidant nutraceuticals in adulthood and aging

The primary objective of this review is to present an integrated analysis of oxidative stress and inflammation, connecting molecular mechanisms with clinical evidence