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Its cytotoxic mode of action is mediated by its interaction with DNA to form DNA adducts, primarily intrastrand crosslink adducts, which activate several signal transduction pathways, including those involving ATR, p53, p73, and MAPK, and culminate in the activation of apoptosis

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Eosinophilic bronchiectasis: a different subtype

Horie T, Shiraiwa T, Homma K, Katsura K, Maeda S, Yoshida H (2005) Can yields of lowland rice resume the increases that they showed in the 1980s
