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the first step is conjugation of glutamic acid and cysteine, which is catalyzed by glutamate-cysteine ligase and generates -glutamyl-cysteine (-Glu-Cys) and the second step is catalyzed by glutathione synthase, which adds glycine to -Glu-Cys, forming glutathione

Tf: Transferrin

CrossRef Insight of novel biomarkers for papillary thyroid carcinoma through multiomics Wei Liu, Junkan Zhu, Zhen Wu, Yongxiang Yin, Qiao Wu, Yiming Wu, Jiaojiao Zheng, Cong Wang, Hongyan Chen, Talal Jamil Qazi, Jun Wu, Yuqing Zhang, Houbao Liu, Jingmin Yang, Daru Lu, Xumin Zhang, Zhilong Ai Frontiers in Oncology.2023;[Epub] CrossRef Identification of NIFTP-Specific mRNA Markers for Reliable Molecular Diagnosis of Thyroid Tumors So-Yeon Lee, Jong-Lyul Park, Kwangsoon Kim, Ja Seong Bae, Jae-Yoon Kim, Seon-Young Kim, Chan Kwon Jung Endocrine Pathology.2023