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It protects existing collagen from degradation by neutralizing the matrix metalloproteinases (MMPs) that break down collagen fibers

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Pierola AA, Assi R, Devendra KC, Abaza Y, Zahr AA, Chamoun K, Montalban-Bravo G, Takahashi K, Jabbour EJ, Kadia T, Ravandi F, Cortes JE, DiNardo CD, Daver N, Borthakur G , Pemmaraju N, Konopleva M, Bueso-Ramos CE, Patel KP, Futreal A, Pierce S, Kantarjian HM, Garcia-Manero G

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