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Like vincristine, paclitaxel does not directly affect mitochondrial DNA, but nonetheless induces swollen and vacuolated mitochondria in both myelinated and unmyelinated sensory axons in the saphenous nerve (Flatters and Bennett, 2006)
Effect of TACI signaling on humoral immunity and autoimmune diseases
Conclusion: Sublingual and oral B12 supplementation appear to be as effective as intramuscular (IM) injections in improving cobalamin status and reducing homocysteine levels
They also have a thorough understanding of proper dosages and are able to identify and address any contraindications based on your medical history
Parisy et al., 2007)
