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The animals were housed in cages of five animals each, under controlled conditions of temperature (25C 1C) with a 12-h light/dark cycle, and had access to water and food ad libitum

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All the isoforms of vitamin E have immunomodulatory and anti-inflammatory properties [399,400] by inhibiting the release of pro-inflammatory cytokines, such as interleukin (IL)-1, IL-6, or tumor necrosis factor (TNF) [399,400]

However, because of the episomal nature of the adenoviral and AAV vectors after cell entry, these viral vectors are most suited for therapeutic applications requiring only transient expression of the transgene (Russell, 2000, J

Despite research reporting physiological potential similar to the parent protein, Receptor Grade IGF-1 LR3 does not appear to interact with IGF binding proteins (IGFBPs) as strongly as IGF-1