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Among the agents that mediate their effects through S -glutathionylation, NOV-002 has been most extensively studied, with a phase III trial (NCT00347412) completed in advanced NSCLC [104], and data available from phase II trials in breast and ovarian cancers [105]

Modulation of Pituitary Thyrotropin Releasing Hormone Receptor Levels by Estrogens and Thyroid Hormones

10.1016/j.neuropharm.2017.12.030 88 KarelsonE.BogdanovicN.GarlindA.WinbladB.ZilmerK.KullisaarT.et al

This report shows a path towards large-scale production of exosomes, a major issue for broad therapeutic application, using a 3D cell culture bioprocessing method

102, no
