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Similarly, TB-500 has undergone extensive safety evaluation including human research trials showing safety at intravenous doses up to 1,260 mg equivalent, with no dose-limiting toxicities or serious adverse events attributable to the peptide in carefully controlled studies

Similarly, a meta-analysis of blood and salivary cortisol levels in early psychosis patients found elevated blood cortisol levels and attenuated cortisol awakening response in FEP but not in high-risk individuals [45]

however, persistent metabolic stress progressively impairs this process, promoting triglyceride accumulation, inflammation, and hepatocellular injury

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Autism Res Rev Intl 2000
