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This reprogramming results in global hypomethylation and significant loss of genetic memory, which is foundational for acquiring pluripotency and redetermining cell fate
& Taeb, A
M., Adhihetty P
Additionally, overexpression of alpha-synuclein increases the phosphorylation of NMDARs, thereby increasing the expression of NR1 and NR2B subunits and increasing the sensitivity of NMDARs to glutamate excitotoxicity (Yang et al., 2016)
Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease
