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10 Due to impaired metabolic clearance, heavy alcohol use may increase estrogen levels and breast cancer risk

Optimal results require combining the peptides cellular effects with appropriate nutrition providing caloric deficit, regular cardiovascular exercise to oxidize mobilized fatty acids, and resistance training to preserve muscle mass during fat loss

This is consistent with other studies that have noted that C R is not always present within atypical 2-Cys PRXs 41

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The compelling animal research creates obligation to conduct proper human studies, not license to experiment outside formal research oversight