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Furthermore, 2012 displayed excellent in vivo pharmacokinetics, and greatly reduced tumor burden in the B16F10 melanoma mouse model

Quantitative sensory testing (QST) provides psychophysical measures of thermal and pain thresholds, while epidermal nerve fiber density (ENFD) analysis via punch skin biopsy offers a histopathological index of small fiber degeneration [46] (Table 1)

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use under a doctors guidance may be safe

What the animal data cannot tell us is what happens in humans