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Description
Studies have found that HFD can stimulate pro-inflammatory signaling cascades, increase cytokines (TNF-, IL-1, IL-6, and IFN-) that disrupt the barrier, and decrease cytokines (IL-10, IL-17, and IL-22) that promote barrier formation, thereby enhancing intestinal permeability

J Clin Oncol (2015) 33:21128

RULE1 claimed supply shortages when we asked why there was inconsistency in its ingredient sourcing, but other companies seem to have no problem consistently producing vegan BCAAs

doi: 10.1093/gerona/59.2.M178

& Shafer, O