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These patients are on a Pernicious Anaemia hospital ward where they were kept alive by eating just cooked or raw liver And imagine the further joy when a decade or so later they were provided with a monthly injection of grown B12

Expected timeline based on research: Initial vascular effects may begin within the first week

This makes 5mg a clinically meaningful dose, not just a stepping stone to higher doses

Education into practice Practice How often do you evaluate B 12 deficiency related symptoms in individuals at high risk of developing this, such as vegetarians and vegans, or people with increased risk of B 12 malabsorption, such as individuals with type 1 diabetes or Hashimoto hypothyroidism

It is the stability limit