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Gonzalez-Latapi, P

Elesclomol is widely recognized to induce copper overdose and cell death (139), by acting as a copper ion carrier with a hydrophilic pore in its centre, to which Cu2+ ions can bind easily, facilitating copper entry into cells, thus increasing the intracellular copper concentration (140), and this, in-turn increases ROS levels, triggering oxidative stress (141) and ultimately cell death

This suggests that vitamin K2 may not be effective in reversing existing calcification

Molecular Mechanisms and Potential Therapeutical Targets in Huntington?s Disease