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Nevertheless, conflicting views persist regarding the precise mechanistic pathways driving liver injury, with earlier reports emphasizing apoptosis, caspase-independent cell death, the ubiquitin-proteasome system, or ROS involvement [54]
Guggino SE, Aronson PS
Folic acid supplementation is known to prevent the folate trap
The low level of CoQ10 contributes to mitochondrial dysfunction and the generation of ROS and lipid peroxidation [1113]
