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Clin Pharmacol Ther 83 , 160166, (2008)

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Furthermore, in rats that are subjected to cecum ligation and puncture (CLP) induced-AKI, early glomerular syndecan-1 loss is followed by the loss of hyaluronic acid 7 h after CLP is initiated, and this is accompanied by alterations in glomerular sialic acids and the molecular composition of the glomerular filtration barrier (95)

This helps determine whether peptide therapy such as BPC-157 is appropriate and identifies any contraindications before initiating treatment