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2.2.1 Oxidative stress and mitochondrial dysfunction METH significantly increases the production of ROS and reactive nitrogen species, overwhelming antioxidant defenses in neurons

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When predictions were based on stromal biomarker expression, NAC responders in the NAC cohort exhibited a trend toward prolonged OS ( P = 0.063) and significantly longer PFS ( P = 0.015) compared with nonresponders (Supplementary Fig

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