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As expected, combined treatment of DSF and Cu significantly increased cellular ROS levels (Fig

At cellular and molecular level, curcumin is able to regulate various signaling and signal molecules, such as cytokines, transcription factors, enzymes, growth factors, apoptotic proteins, inflammatory mediators, protein kinases, and cell cycle proteins (Carolina Alves et al., 2019

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doi: 10.1016/j.neuroscience.2004.09.057