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Usually, the HE syndrome produces neuropsychiatric symptoms which manifest themselves from mild to severe, with coma as the ultimate sequelae
A 2025 systematic review (Vasireddi et al.) and a 2025 narrative review both concluded that while the regenerative signal in animals is compelling, robust human clinical evidence is lacking
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A deficiency in B12 can lead to fatigue, weakness, and even developmental delays in infants
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