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Acetyl-l-carnitine is a first-in-class epigenetic regulator of genes involved in analgesic action such as the metabotropic glutamate 2 [mGlu2] receptor gene, neurotrophic factors, and antioxidant enzymes (e.g., superoxide dismutase) (Fig

While commonly available in oral form, L-Carnitine is only truly effective when administered via injection, as the bodys ability to absorb it through the digestive tract is extremely limited

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