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Because of the glycolytic conversion of glucose to lactate in tumor cells, the tumor microenvironment has been demonstrated to be somewhat acidic (pH 6.07.0), lowering the pH value from that of normal tissues (pH 7.4) and has been exploited to develop pH-sensitive drug liposomes
But she had a sneaky culprit dragging her down: shin splints
Biochimica et Biophysica Acta 1822, 822829
Science 366:eaar5551
TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma
