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[DOI] [PubMed] [Google Scholar] Bentez-Mateos A

Proc (bayl Univ Med Cent) 13(4):421423

In this work, by noting that pre-equilibration of ligand-receptor and ternary complex formation occur faster than the receptor internalization and downregulation, we formulate a minimal kinetic model to offer a semi-quantitative yet predictive understanding of the GPCR desensitization and down-regulation

Spermidine is a polyamine whose concentration can reach the millimolar range in the intracellular environment, while extracellularly it is present in the low micromolar range (Heller et al., 1978

For now, the existing thyroid treatment paradigm leaves a lot to be desired, which means extra help outside of traditional medications and treatments is often needed