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BBA Clin 1: 1223, 2014

In VaD, an insufficient oxygen supply to the brain, reduced blood flow, and decreased intracellular oxygen partial pressure result in mitochondrial oxidative phosphorylation dysfunction, inhibition of protein synthesis, insufficient ATP production, and energy depletion, ultimately leading to sodium-potassium pump failure, calcium overloading, and disturbances in cytosolic ions (e.g., Ca 2+ , Na + , H + , ROS), which subsequently increase

Swalwell, H., Latimer, J., Haywood, R

Ligand for translocator protein reverses pathology in a mouse model of Alzheimer's disease

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