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2.5 Treatment Cognitive-behavioral therapy (CBT) is a well-established standard treatment for addressing cognitive impairment caused by METH abuse ( In addition to behavioral therapies, pharmacological approaches have demonstrated potential benefits

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Triple agonists [12] such as GLP-1RA, GIP-RA plus glucagon-RA are in development and may show comparable efficacy in weight loss to tirzepatide by targeting multiple pathways involved in energy regulation [13]

Benchmarking and Preclinical Evaluation of Drug Candidates Preclinical drug and target discovery for obesity is a highly competitive area