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The brain requires specific building blocks to construct new neurons and synapses: omega-3 fatty acids for cell membranes, B vitamins for myelination, zinc and magnesium for enzymatic processes

And elevated NAD+ activates sirtuins (especially SIRT1 and SIRT3), the enzymes that shift cellular metabolism from carbohydrate dependence to fat oxidation

doi: 10.1016/j.bbi.2008.06.005

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Conservative Approaches Conservative treatments are often the first step