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In the context of tumorigenesis, glutamine-derived 2-HG alters the epigenetic landscape of chromosomes and induces oncogenic transformation

Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy

Singarayar MS, Chandrasekaran A, Balasundaram D, Veerasamy V, Neethirajan V, Thilagar S, Prebiotics

DNPH readily forms hydrazones and exhibits enhanced D/I upon protonation and sodiation, without the need for standard matrix addition

doses can act locally pro-oxidant (Fenton-like) with potential anti-tumor cytotoxicity
