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Any suspected adverse reactions to medicines can be reported through the MHRA Yellow Card scheme

The MTHFR enzyme is responsible for converting tetrahydrofolate into 5-methyltetrahydrofolate (5-MTHF), and reduced enzyme activity may influence methylation efficiency, particularly if riboflavin (vitamin B2) status is suboptimal

HuYYeZSheYLiLWuMQinKet alEfficacy and safety of probiotics combined with traditional chinese medicine for ulcerative colitis: a systematic review and meta-analysis

Cell Biochem Funct 36(6):292302