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Abnormal mitochondrial morphology can inhibit mitochondrial OXPHOS and alter calcium homeostasis and mitochondria-mediated apoptosis, leading to mitochondrial dysfunction and mitochondria-related diseases (91)

Sem Liv Dis 25: 93104

Research status Reta is Phase 3 investigational

The estimated median prevalence for North America and Europe is 65.5/10,000 and 61.9/10,000, respectively [25]

second, focusing on high-risk cohorts, such as patients with MASH-related compensated cirrhosis, using dynamic contrast-enhanced ultrasound (DCE-US) to monitor de novo nodule emergence and evolution (e.g., arterial phase hyperenhancement) as surrogate endpoints for preliminary chemopreventive assessment