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Bax oligomerization is associated with the formation of openings in the OMM to allow the release of cytochrome c and other IMS proteins into the cytosol, and hence Bax oligomerization is considered a critical regulatory point in cell death (Youle and Strasser, 2008)

The role of DNA repair in brain related disease pathology

Lack of approval reflects insufficient human clinical trial data and incomplete evaluation of risks, dosing, and long-term effects

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