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According to the Catalogue of Somatic Mutation in Cancer (COSMIC) database, NF1 is among the 20 most frequently mutated genes in GBC, with a somatic mutation frequency of 5%, based on the sequencing of nearly 300 samples (Fig

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Trends Neurosci 29:257262

All of the predictors (tpos, tneg, cpos, and cneg) have statistically significant effects on the dependent variable, according to statistical analysis ( Table 3 )

For instance, while statins have shown anti-inflammatory properties in some autoimmune conditions, their long-term safety and efficacy in SS, particularly in patients with pre-existing liver conditions or muscle-related side effects, require further investigation
