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Valente et al., 2004)

Result: Microbial imbalance in asthma patientsmarked by reduced -diversity, depletion of immunomodulatory taxa (e.g., Bifidobacterium, Faecalibacterium), and enrichment of pathobiontsdisrupts short-chain fatty acid (SCFA) and tryptophan metabolism, skewing Th17/Treg balance toward Th2-dominated inflammation and airway hyperresponsiveness

Deletion of ALOX15 could obviously limit lipid peroxidation and increase GSH levels in cardiomyocytes subjected to ischemic [18]

Why target senescent cells

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