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This increase in ROS activates the NF-B pathway by oxidatively modifying I-kappa-B-kinase beta (IKK), inducing the release of IL-1 and TNF-

doi: 10.3389/fimmu.2024.1520441 191 AlqahtaniSMAfzalMAfzalOAlabbasAPhalakPGoyalK

Available from: [DOI] [PMC free article] [PubMed] [Google Scholar] 50.He X, Yang Y, Mu L, Zhou Y, Chen Y, Wu J, et al

6,239 Recently, researchers have reported that the Wnt/-catenin pathway collaborates with AHCTF1 (also known as ELYS) to act as a superenhancer-mediated gene to drive colon cancer

The activation of this signaling pathway can regulate various physiological functons of cells, such as anti-inflamatory, antioxidant, promoting cell proliferation and differentiation, etc