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Holy basil, often referred to as Ocimum tenuiflorum or Ocimum sanctum , has long been a staple in Ayurveda for its stress-relieving properties

Therefore, the abnormality of glial cells may damage mitochondrial function, leading to the insufficient energy supply of DA neurons and eventually their death

When PNP was inhibited pharmacologically by the compound immucillin H (ImmH), intracellular cleavage of NR to NAM was prevented, and NAD + synthesis was potentiated from NR both in vitro and in vivo 25

Oxidative burst during inflammatory processes triggers the formation of both superoxide and nitric oxide radical from immune cells and they react together to produce the highly reactive peroxynitrite anion radical which is a potent oxidizing agent that can cause DNA fragmentation [5,7,22]

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