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coli H10407 strain, O55:H7 strain, CB9615, BW2952 strain, and K-12 strain DH10B sub-strain indicated their curcumin converting ability

Marani M, Tenev T, Hancock D, Downward J, Lemoine NR

Nutrition (Burbank, Los Angeles County, Calif.) , 124 , 112427

Formononetin, an isoflavone compound derived from Astragalus membranous, has been extensively studied for its diverse pharmacological effects including anti-inflammatory, anti-oxidative, and anti-tumorigenic properties (Yu et al., 2022)

So, unlike the organometallics, relatively weak nucleophiles such as halides, cyanide ion, thiols, alcohol, and amines, perform 1,4-addition: One notable exception in organometallics is the reaction of organocuprates which are not as strong and therefore, they occur in 1,4-fashion: Check out this comprehensive review of the reaction of Grignard (RMgX), Organolithium (RLi), and Gilman (R 2 CuLi) Reagents to understand how they differ in their addition to carbonyl compounds and other electrophilic species
